Systems and Synthetic Biology - Network Medicine and Pharmacology

医学科学与临床医学
一万年文明- 从农业起源到城市发展，而到未来太空生态城市 - 大健康产业，在人工智能与生物技术上的整合模式。
1-社会-心理-生物医学模式，心身关系与行为医学框架 - 生态环境，伦理规范与健康管理。
2-系统与合成生物学 - 纳-微流控芯片技术解决方案。
3-个体化与转化医学 - 精准检测与基因-细胞治疗体系。
Medical Science and Clinical Medicine
Ten thousand years of civilization - From the origins of agriculture to urban development, and to future space eco-cities - The great health industry, the integration model of artificial intelligence and biotechnology.
1-Biopsychosocial model, psychosomatic relationship and behavioral medicine framework - Ecological environment, ethical norms and health management.
2-Systems and synthetic biology - Nano-microfluidic chip technology solution.
3-Personalized and translational medicine - Precision detection and gene-cell therapy system.

医学发展概览
1-经济发展模式的转型 - 庄园与手工业作坊，标准化与工业流程，分工协作的组织化。
2-医学的人文与科学 - 传统文化与现代科学，人文学问与管理实践 - 企业管理与技术创新。
在医学上，从哈维生理学与C.贝尔纳实验医学方法，发展到生态系统与健康科学和大数据与个体化治疗。
在制造上，从发酵工艺与菌种选育到基因重组与合成生物技术发展，并形成了物理硬件-数字软件和生物湿件融合的机器人架构。
Overview of Medical Development
1-Transformation of economic development models - manors and handicraft workshops, standardization and industrial processes, organization of division of labor and cooperation.
2-Humanities and science in medicine - traditional culture and modern science, humanities and management practice - enterprise management and technological innovation.
In medicine, it has evolved from Harvey's physiology and C. Bernard's experimental medical methods to ecosystem and health science, as well as big data and personalized treatment.
In manufacturing, it has progressed from fermentation processes and strain selection to genetic recombination and synthetic biotechnology, forming a robotic architecture that integrates physical hardware, digital software, and biological wetware.

系统生物技术 - 细胞分析与合成-
1-细胞模型与工程细胞 - 细胞通讯与分子网络拓扑分析，工程细胞设计与合成，细胞传感器与生物反应器。
2-药物分析与分子筛选 - 天然药物次生代谢与网络药理分析，细胞的系统分析与药物分子筛选，疾病发生机理的基因分析。
3-发酵工艺与纯化技术 - 底盘细胞与分选，细胞株系与组织工程，发酵工程与代谢产物提纯技术。
4-受控生态与自动化设计 - 生物制造与工程医学，生物细胞-神经拟态与类脑计算。
Systems Biotechnology - Cell Analysis and Synthesis
1-Cell models and engineered Cells - Cell communication and molecular network topology analysis, design and synthesis of engineered cells, cell sensors and bioreactors.
2-Drug analysis molecular screening - Secondary metabolism of natural drugs and network pharmacology analysis, system analysis of cells and drug molecular screening, genetic analysis of disease mechanisms.
3-Fermentation processes and purification technologies - Chassis cells and sorting, cell lines tissue engineering, fermentation engineering and metabolite purification technologies.
4-Controlled ecology and automation design - Bio-manufacturing and engineering medicine, biological cells-neuromorphic and brain-inspired computing.

生物铸造厂 - 细胞系制备流水线
1-自动化实验室操作流程
数据库与生物信息分析 - 计算机模拟软件，实验数据分析 - 生物设计软件与定向进化。
2-药物分子筛选与代谢工程
系统生物学 - 细胞分析的实验数据与定量模型，合成生物学 - 工程细胞设计与合成的生产流程。
3-人工智能与基因工程结合方法的循环模式
计算机干实验 - 学习与设计，生物技术的湿实验 - 建构与测试。
生物系统与人工生命研究，包括，虚拟和实体的人工进化 - 也叫泛进化，从技术路径与设计艺术到工程实施，1991-2010年Bj.Zeng论述了生物分子和细胞与神经元计算机 - 湿件，并与IC芯片和IT软件整合的产业化模式。
Biofoundry - Cell Line Development Pipeline
1-Automated laboratory operation workflow
Database and bioinformatics analysis - computer simulation software, experimental data analysis - biological design and directed evolution.
2-Drug molecule screening and metabolic engineering
Systems biology - experimental data and quantitative models of cell analysis, synthetic biology - production processes of cell design and synthesis.
3-Cyclical pattern of combining artificial intelligence and genetic engineering methods
Computer dry lab - Learn and Design, biotechnology wet lab - Build and Test.
Research on bio-systems and artificial life, including virtual and physical artificial evolution - also known as pan-evolution, from technical paths and design art to engineering implementation, Bj.Zeng discussed biomolecules and cells with neuron computers - wetware, and the industrialization model integrated with IC chips and IT software from 1991 to 2010.

人工智能与工程生物学的发展
- Bj.Zeng的探索
1983-1987年，结构论 - 泛进化理论，心理-生物学与行为遗传学，拓扑生物学与分子细胞发生学。
1991-2003年，城市群与地缘文化学，生物系统科学与工程 - 理论综合与技术会聚：
1-系统医学与图论-网络拓扑模型 - a-认知与行为系统 - b-神经-内分泌-免疫调控系统 - c-物质-能量代谢系统 - d-繁殖系统。
2-系统遗传学与生物工程 - 人工生物系统与生物电子设计 - 转基因输卵管和细胞仿生工程。
3-人工智能-基因工程与人工进化 - 计算生物信息学与实验生物技术。
2008-2010年，神经元计算机和纳-微流控技术与有机（organic）机器人。
2023-2025年，合成神经遗传学 - 另类意识与人机协同进化。
注：
引用了1910年合成（化学）生物学和1968年系统（数学）生物学词汇的相关文献，转换到偶合的方法体系。
Development of Artificial Intelligence and Engineering Biology
- Bj.Zeng's Exploration
1983-1987, structurity - pan-evolutionary theory, psycho-biology and behavioral genetics, topological biology and molecular cytogenesis.
1991-2003, Cities groups and geoculturology, Bio-systems science and engineering - Theoretical synthesis and technological convergence:
1-Systems medicine and graph theory-network topological model - a-Cognitive and behavioral system - b-Neuroendocrine-immune regulatory system - c-Substance-energy metabolism system - d-Reproductive system.
2-systems genetics and bioengineering - artificial biological systems and bioelectronic design - transgenic oviduct and cell bionic engineering.
3-artificial intelligence-genetic engineering and artificial evolution - computational bioinformatics and experimental biotechnology.
2008-2010, neuron computers and nano-microfluidic technology integrated with organic robots.
2023-2025, Synthetic neurogenetics - Alternative consciousness and human-machine co-evolution.
Note:
Relevant literature from synthetic (chemical) biology in 1910 and systems (mathematical) biology in 1968 was cited and converted into the methodological system of coupling.